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Thursday, August 29, 2019

Are You at Risk of Acquiring Acute Kidney Injury?

Are You at Risk of Acquiring Acute Kidney Injury?



Are You at Risk of Acquiring Acute Kidney Injury?




Acute kidney injury (AKI) is an improvised episode of kidney failure or kidney damage (Urinary system) that occurs in a few hours or days. AKI causes an accumulation of waste products in the blood and makes it difficult for the kidneys to maintain the proper balance of fluids in the body

Acute kidney injury (AKI) is defined by impaired renal filtration and excretory function, with consenting retention of nitrogen waste and other products normally eliminated by the kidneys. IAK can also affect other organs such as the brain, heart and lungs. Acute kidney damage is common in patients who are in the hospital, in the ICU and especially in older adults


Are you at risk of acute kidney injury (AKI)? According to studies available from the nephrology community, there have been no AKI series in the past 10 years

Acute kidney injury (ARI)  Definition 


AKI is not a single disease, but is a designation of a group of heterogeneous conditions that share common diagnostic characteristics: in particular, an increase in the concentration of serum creatinine (SCr) often associated with a decrease in the volume of urine. It is important to recognize that AKI is a clinical and non-structural diagnosis. A pacific can have ARF with or without parenchymal damage to the kidneys.

The severity of the AKI can vary from the asymptomatic and transient variation of the laboratory parameters of the glomerular filtration rate (GFR), to the overwhelming and rapidly fatal in the effective regulation of the circulating volume and of the electrolytic and acid base composition of the plasma. There are many different causes for this. condition with prescription reduced kidney function. Because of its vault it carries an increased risk of disease and even death. In addition, ARF has also been linked to chronic kidney disease. This syndrome can be caused by any of the following: burns, shock, drug toxicity, sepsis, trauma, severe diarrhea and use of contrast by intravenous imaging procedures

Acute kidney injury (ARI) Symptoms 


One of the notable symptoms is frequent or less frequent urination, as well as night urination. Urine may also be pale or even discolored and may have blood. You persist with this condition in post experiencing pressure and difficulty urinating or abnormal amounts of urine. I will hold an extremely vital possibility, because it is a very serious health problem and I will address it immediately. When I was not properly caught in the parrot and rhyme in excess liquid, a person could be noticed based on the other part of the body:

  • Swelling of legs, ankles, feet, hands and face
  • Darkening of the skin
  • Loss of appetite, difficulty sleeping
  • Excess protein in the blood
  • Shortness of breath, due to the lack of fluid in the lungs

Acute kidney injury (ARI) Causes


Pathophysiology :

The causes of ARI have traditionally been divided into three categories: 
  • Prerenal azotemia
  • Intrinsic parenchymal renal disease 
  • Postrenal obstruction

Prerenal asotemia: 

Prerenal azotemia (from "azo", which means nitrogen, and "-emia", which means in the blood) is the most common form of AKI. It is the designation for an increase in SCr or BUN concentration due to inadequate renal plasma flow and intraglomerular hydrostatic pressure to support normal glomerular filtration

Intrinsic parenchymal renal disease or Intrinsic AKI: 


The most common causes of intrinsic AKI are sepsis, ischemia and nephrotoxins, both endogenous and exogenous. In many cases, prerenal azotemia progresses to tubular lesions. Although classically defined as "acute tubular necrosis", the human biopsy confirmation of tubular necrosis is, in general, often scarce in cases of sepsis and ischemia; in fact, processes such as inflammation, apoptosis and alteration of regional perfusion can be important pathophysiological factors

Posttrenal AKI: 


Posttrenal AKI occurs when normally unidirectional urine flow is blocked acutely, partially or completely, leading to increased retrograde hydrostatic pressure and interference with glomerular filtration. Obstruction of urinary flow can be caused by functional or structural disturbances anywhere from the renal pelvis to the tip of the urethra


Acute kidney injury (ARI) Diagnosis 


In the emergency department, the objectives are to identify patients at risk of acute kidney damage who are obviously not ill and those who have been diagnosed with kidney damage to correct metabolic effects, reduce ongoing kidney damage and prevent iatrogenic damage. Determine whether the kidney injury is prerenal, postrenal or intrinsic


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